High Force Research has extensive experience in the synthesis and development of fluorescent molecules for use as cell-specific imaging agents.
Working in collaboration with Durham University we have also developed a range of novel fluorescent retinoids based on the natural retinoid ATRA (All-Trans Retinoic Acid). Our retinoid derivatives are stable and also intrinsically fluorescent. They can function as both a biologically active retinoid and at the same time act as a visual probe.
Imaging applications for the use of these novel compounds in cell biology range from visualisation and localisation to monitoring real-time concentration and local environments.